Laboratory tests are of limited usefulness in the diagnosis of microscopic colitis; it may show a mild anemia, a moderate increase in ESR and CRP therefore, not pathognomonic signs.
There is only one exam that is the instrumental diriment PANCOLONSCOPIA accompanied by biopsies at the bottom of the caecal livvello, ancestor, the transverse and sigmoid-rectum.
The drawings are indispensable as microscopic colitises in endoscopic signs are absent and only histological examination show that damaged epithelial cells with accumulations of intraepithelial lymphocytes and increased sub-epithelial collagen will make a definitive diagnosis. I Furthermore, posted will be prepared for immunohistochemical study.
Histological picture which shows lymphocytic infiltration in
subepithelial layer of the epithelium and lamina of the colon in microscopic colitis.
The Microscopic colitis is a rare disease of difficult clinical confirmation, to generally be benign but must be diagnosed quickly as the non-treatment can dramatically worsen the quality of life of older people often already plagued by comorbidity.
The only way to make sure diagnosis is to perform a phantasmoscopia with biopsies throughout the colon thus:
In elderly patients with a history of recurrent watery diarrhea, a colonoscopy must never forget the biopsy at the level of each section of the bowel in the presence of a normal endoscopic picture.